Adipocyte membrane phospholipids and PPAR-g expression in obese women: relationship to hyperinsulinemia
نویسندگان
چکیده
NEZHA ZEGHARI, HUBERT VIDAL, MOHAMED YOUNSI, OLIVIER ZIEGLER, PIERRE DROUIN, AND MIREILLE DONNER Equipe Accueil 2402, Université Henri-Poincaré, 54500 Vandoeuvre les Nancy; Institut National de la Santé et de la Recherche Médicale Unité 449, Faculté de Médecine Laënnec, 69000 Lyon, France; Service de Diabétologie, Maladies Métaboliques et Nutrition and Centre d’Investigation Cliniques Inserm-Centre Hospitalier Universitaire de Nancy, 54520 Dommartin les Toul, France
منابع مشابه
Adipocyte membrane phospholipids and PPAR-gamma expression in obese women: relationship to hyperinsulinemia.
We have shown that membrane sphingomyelin (SM) is an independent predictor of the variance of fasting plasma insulin (FPI) concentrations and the homeostasis model assessment (HOMA) estimate of insulin resistance in obese women. The peroxisome proliferator-activated receptor-gamma (PPAR-gamma) is a key component in adipocyte differentiation that may also contribute to the sensitivity of cells t...
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